Joseph P Mathew Selected Research

Postoperative Cognitive Complications

1/2021	Cerebrospinal Fluid Proteome Changes in Older Non-Cardiac Surgical Patients with Postoperative Cognitive Dysfunction.
11/2019	Flow Cytometry Characterization of Cerebrospinal Fluid Monocytes in Patients With Postoperative Cognitive Dysfunction: A Pilot Study.
1/2019	Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial.
1/2019	The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.
1/2018	18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery.
1/2017	Resting-State Functional Connectivity and Cognition After Major Cardiac Surgery in Older Adults without Preoperative Cognitive Impairment: Preliminary Findings.
6/2014	Arterial hyperoxia during cardiopulmonary bypass and postoperative cognitive dysfunction.
12/2013	Intraoperative magnesium administration does not improve neurocognitive function after cardiac surgery.
9/2013	Cortical β-amyloid levels and neurocognitive performance after cardiac surgery.
12/2011	Population pharmacokinetics of lidocaine administered during and after cardiac surgery.

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Joseph P Mathew Research Topics

Disease

13	Postoperative Cognitive Complications 01/2021 - 07/2002
13	Cognitive Dysfunction 01/2019 - 07/2002
11	Inflammation (Inflammations) 01/2021 - 02/2003
11	Atrial Fibrillation 01/2019 - 02/2002
8	Acute Kidney Injury (Acute Renal Failure) 12/2022 - 03/2003
5	Heart Failure 01/2013 - 10/2003
5	Cardiovascular Diseases (Cardiovascular Disease) 06/2011 - 06/2003
5	Stroke (Strokes) 09/2005 - 01/2002
4	Hypothermia 01/2019 - 02/2004
4	Hemorrhage 01/2016 - 12/2007
4	Myocardial Infarction 05/2015 - 06/2003
4	Atherosclerotic Plaque (Atheroma) 06/2007 - 01/2003
3	Brain Injuries (Brain Injury) 01/2022 - 04/2010
3	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2022 - 10/2021
3	Alzheimer Disease (Alzheimer's Disease) 12/2021 - 01/2016
3	Delirium 01/2020 - 06/2015
3	Neuroinflammatory Diseases 01/2019 - 01/2017
3	Heart Arrest (Cardiac Arrest) 01/2019 - 01/2011
3	Ischemia 02/2016 - 08/2005
2	Critical Illness (Critically Ill) 12/2022 - 01/2020
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2021
2	Shock 12/2021 - 01/2020
2	Neurocognitive Disorders (Clerambault Syndrome) 01/2021 - 12/2018
2	Hypotension (Low Blood Pressure) 01/2017 - 03/2014
2	Nervous System Diseases (Neurological Disorders) 06/2015 - 10/2004
2	Mitral Valve Insufficiency (Mitral Regurgitation) 06/2014 - 08/2005
2	Anemia 03/2014 - 10/2003
2	Out-of-Hospital Cardiac Arrest 06/2012 - 01/2011
2	Body Weight (Weight, Body) 12/2011 - 02/2007
2	Thrombosis (Thrombus) 05/2007 - 06/2003
2	Reperfusion Injury 08/2005 - 06/2003
2	Hyperthermia 06/2005 - 09/2004
2	Atherosclerosis 08/2004 - 04/2004
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2022
1	Multiple Organ Failure (MODS) 10/2021
1	COVID-19 03/2021
1	Cardiac Arrhythmias (Arrythmia) 10/2020
1	Coma (Comas) 01/2020
1	Hemorrhagic Shock 01/2019
1	Ventricular Fibrillation 01/2019
1	Multiple Trauma (Multiple Injuries) 01/2019
1	Thrombocytopenia (Thrombopenia) 09/2018
1	Pneumonia (Pneumonitis) 01/2018
1	Emergence Delirium 01/2017

Drug/Important Bio-Agent (IBA)

8	CreatinineIBA 05/2020 - 07/2002
6	Biomarkers (Surrogate Marker)IBA 01/2022 - 04/2010
5	Apolipoprotein E4IBA 12/2021 - 01/2003
4	Lidocaine (Xylocaine)FDA LinkGeneric 01/2019 - 03/2009
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2016
3	Amyloid (Amyloid Fibrils)IBA 01/2018 - 09/2013
3	Biological ProductsIBA 03/2016 - 05/2007
3	MagnesiumIBA 10/2015 - 06/2003
3	C-Reactive ProteinIBA 05/2007 - 07/2005
3	Interleukin-6 (Interleukin 6)IBA 04/2007 - 02/2003
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 12/2022 - 01/2022
2	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 12/2022 - 01/2022
2	Peptides (Polypeptides)IBA 01/2021 - 01/2019
2	CytokinesIBA 01/2017 - 04/2007
2	Anesthetics (Anesthetic Agents)IBA 01/2017 - 06/2010
2	Isoflurane FDA LinkGeneric 01/2017 - 01/2016
2	Propofol (Diprivan)FDA LinkGeneric 01/2017 - 01/2016
2	ApolipoproteinsIBA 06/2015 - 08/2004
2	von Willebrand FactorIBA 10/2014 - 12/2007
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 07/2012 - 04/2004
2	omega-Chloroacetophenone (Mace)IBA 06/2011 - 06/2003
2	adhesion receptorIBA 07/2005 - 03/2003
1	Oxygen (Dioxygen)IBA 01/2022
1	Vasopressins (Vasopressin)IBA 03/2021
1	Eicosapentaenoic AcidIBA 01/2021
1	Docosahexaenoic AcidsIBA 01/2021
1	Arachidonic Acid (Vitamin F)IBA 01/2021
1	LipidsIBA 01/2021
1	ProteomeIBA 01/2021
1	CannabinoidsIBA 01/2020
1	Platelet Activating FactorIBA 01/2020
1	CCR2 ReceptorsIBA 11/2019
1	HMGB1 Protein (HMG1)IBA 01/2019
1	Neuroprotective AgentsIBA 01/2019
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2019
1	Type A Botulinum Toxins (Botox)FDA Link 01/2019
1	Caspase 3 (Caspase-3)IBA 01/2019
1	Annexin A1IBA 01/2019
1	Intergenic DNA (Junk DNA)IBA 09/2018
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 09/2018
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2018
1	florbetapirIBA 01/2018
1	MercuryIBA 01/2017

Therapy/Procedure

28	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 09/2018 - 02/2002
19	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2019 - 01/2003
8	Therapeutics 12/2022 - 04/2004
5	Length of Stay 01/2022 - 03/2004
5	Anesthesia 01/2019 - 01/2016
4	Rewarming 01/2019 - 01/2002
2	Induced Hypothermia 06/2012 - 01/2011
1	Cardiac Surgical Procedures 12/2022
1	Critical Care (Surgical Intensive Care) 10/2021
1	Heart Transplantation (Grafting, Heart) 10/2020
1	Sympathectomy (Sympathectomies) 10/2020
1	Catheter Ablation 10/2020
1	Resuscitation 01/2019